Virulence of Streptococcus pneumoniae serotype 6C in experimental otitis media
نویسندگان
چکیده
منابع مشابه
Streptococcus pneumoniae serotype 6C: an intra- and interclonal complex comparison.
We report the annotated draft genome sequences of four serotype 6C Streptococcus pneumoniae isolates of differing genetic backgrounds. Serotype 6C isolates are increasing in prevalence and becoming progressively more resistant to antibiotics. As a result, these strains are likely to become more important in the near future.
متن کاملOccurrence, distribution, and origins of Streptococcus pneumoniae Serotype 6C, a recently recognized serotype.
The prevalence of Streptococcus pneumoniae serotype 6C, a recently recognized serotype that cross-reacts serologically with serotype 6A, was investigated. Isolates of serotype 6A in various collections were recovered, and serotype 6C was differentiated from 6A by multiplex PCR of DNA extracts by using appropriate primers. Antimicrobial susceptibility was performed by Clinical and Laboratory Sta...
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We read the papers of Bratcher and Nahm (3) and Oftadeh et al. (8) with interest. Both papers reported that Streptococcus pneumoniae serotype 6D isolates react with factor antiserum specific to serotype 6C in addition to that to 6B. Pneumococcal serotype 6C, first reported in 2007, cross-reacts serologically with serotype 6A but is differentiated by a change in the wciN gene (wciN ) among the c...
متن کاملStrain-Specific Virulence Phenotypes of Streptococcus pneumoniae Assessed Using the Chinchilla laniger Model of Otitis Media
BACKGROUND Streptococcus pneumoniae [Sp] infection is associated with local and systemic disease. Our current understanding of the differential contributions of genetic strain variation, serotype, and host response to disease phenotype is incomplete. Using the chinchilla model of otitis media [OM] we investigated the disease phenotype generated by the laboratory strain TIGR4 and each of thirtee...
متن کاملMolecular epidemiology of Streptococcus pneumoniae mediated otitis media.
Streptococcus pneumoniae is leading cause of bacterial otitis media in young children. Increasing rates of antibiotic resistance and the changing epidemiology of pneumococcal strains dictate the need to develop new methods to study, control, and prevent these important infections. Investigation into the molecular epidemiology of these bacteria will provide important insights into disease; progr...
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ژورنال
عنوان ژورنال: Microbes and Infection
سال: 2012
ISSN: 1286-4579
DOI: 10.1016/j.micinf.2012.02.008